CED Spike2 Software v9 for Windows

Price: $3150.00


FLEXIBLE. COST-EFFECTIVE. TIME-SAVING

Multichannel, continuous data acquisition and analysis package for stimulus generation,
data capture, scrolling or triggered displays, control of external equipment, and custom analysis.

CED 1902 Amplifiers and Accessories

Life Sciences Data Acquisition and Analysis System

Spike2 is a multi-channel continuous data acquisition and analysis package. Uses range from a simple chart recorder to complex applications requiring stimulus generation, data capture, scrolling or triggered displays, control of external equipment and custom analysis. This flexibility makes it ideal for applications in many fields including electrophysiology, neurophysiology, cardiovascular and respiratory studies.

Spike2 contains recording and analysis features suitable for a wide range of applications. Among the most popular features is it’s built in script language that can automate repetitive tasks and be used for customized protocols; and that it can import and export data to and from many common file types, including MatLab. These powerful data capture and analysis functions, together with one of the CED1401 family of laboratory interfaces, make Spike2 an extremely flexible, cost-effective and time-saving addition to any laboratory.

Features

  • Navigate through your data quickly and simply using the intuitive user interface
  • Record multiple data types, including waveforms, event times, coded markers, and discriminated single or multi-unit spike data
  • Generate simple and complex protocols of waveform and pulse outputs
  • Detect features automatically or manually and take measurements based on triggered and cyclical data
  • Analyze multiple channels of waveform and event data on-line and off-line
  • Display and export images as you want them
  • Expandable by synchronizing multiple CED 1401s
  • Replay data files, with simultaneous output of waveform data

Data Acquisition Using a CED 1401

  • Set different waveform sample rates per channel
  • Capture and classify single and multi-unit spike activity in real-time
  • Continuous, internally timed and triggered recording modes
  • Record multimedia video and sound, time-locked to Spike2 data
  • Store up to 8 channels of event data with microsecond timing resolution
  • Log accurately-timed coded 8-bit digital inputs
  • Annotate data records with text notes and keyboard markers
  • Calibrate waveforms with multiple methods including values, areas, slopes
  • Automatically save and sequence multiple files with optional trigger start
  • Recover data files in the event of an un-commanded system shutdown

Processing and Analysis

  • Waveform analyses including averaging, power spectra and waveform correlations
  • Event analyses including INTH, PSTH, auto and cross correlations and phase histograms
  • Automatically find data features in evoked, spontaneous activity and cyclical data
  • Generate XY plots and data measurements based on cursor feature detection measurement values
  • Process waveforms dynamically on- and off-line.
  • Digitally filter waveforms (FIR and IIR) with interactive filter design -
  • Interactively fit data with functions including exponential, Gaussian, polynomial, sinusoid and sigmoid

Examples of Spike2

Multi-channel on-line spike discrimination with 'spike monitor' display

Multi-channel on-line spike discrimination with 'spike monitor' display>

Script driven detection and classification of seizure activity in EEG

Script driven detection and classification of seizure activity in EEG

Response of insect auditory receptor to pure tone stimuli and calling song

Response of insect auditory receptor to pure tone stimuli and calling song

Scripted sleep stage scoring and analysis

Scripted sleep stage scoring and analysis

Experiment control and stimulus sequencing

The Spike2 output sequencer can run complex experiment control and stimulus sequencing protocols during data capture using up to 16 TTL and 8 waveform outputs. Timing is precise as it is controlled at the CED 1401 interface, not the host computer.

Spike2 graphical sequence editor showing different outputs and additional control options

Spike2 graphical sequence editor showing different outputs and additional control options

Spike detection and sorting

Spike2 identifies and sorts single and multi-unit activity both on- and off-line. It can mark events using simple threshold crossings or sort up to 32 channels on-line with whole wave spike shape template matching of single trace and n-trode data. For multi-unit recordings, Spike2 contains tools for sorting spikes based on the spike waveform shape. A combination of template matching and cluster cutting based on Principal Component Analysis (PCA), user-defined measurements correlations or errors is then used to sort spikes into different units. Spikes can also be sorted interactively. Spike Collision Analysis can separate unit collisions by comparing the current spike shape with pairs of existing templates.

Multi-unit spike discrimination using PCA clustering

Multi-unit spike discrimination using PCA clustering

Catalog # Name Price
953000
Single License
Price: $3,150.00
953020
Additional License
Price: $1,050.00
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